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HESI Guide

HESI A2 Study Guide: Every Section and What to Expect

In short

The HESI A2 is modular — your school picks which sections you sit. Here's what each one contains and how to prepare for the combination you're given.

9 min read September 6, 2026 By the CinnaEntry team
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The single most important fact about the HESI A2: it is modular. Unlike the TEAS, which is always the same four sections, the HESI Admission Assessment is assembled by your school from a menu. Two applicants can sit "the HESI" and take completely different exams.

The academic sections

  • Reading Comprehension — ~47 items. Passages with main idea, inference, vocabulary in context, and author's tone.
  • Vocabulary & General Knowledge — ~50 items. General and health-adjacent vocabulary.
  • Grammar — ~50 items. Parts of speech, sentence structure, common usage errors.
  • Mathematics — ~50 items. Arithmetic, fractions, decimals, ratios, percentages, and conversions — heavy on dosage-style applied problems.
  • Anatomy & Physiology — ~25 items. Body systems, structures and functions.
  • Biology — ~25 items. Cells, metabolism, molecules, genetics.
  • Chemistry — ~25 items. Atomic structure, bonding, reactions, the periodic table.
  • Physics — ~25 items. Rarely required; check before you study it.

There are also non-academic modules — a Learning Style and a Personality profile — which are not scored in the pass/fail sense and need no revision.

Find out which sections your programme requires before you build a study plan. Studying Physics for a school that doesn't test it is a fortnight wasted; skipping A&P for one that does is fatal.

The most commonly required combination

Most nursing programmes ask for some subset of: Reading, Vocabulary, Grammar, Mathematics, and Anatomy & Physiology. A&P is the one that most often carries its own minimum score, and it is the section applicants most often underestimate.

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Scoring

You get a percentage per section and a cumulative score. Most programmes want 75%+, with competitive ones looking for 85–90%. Some set a separate, higher floor on A&P or Maths. There is no penalty for wrong answers, so answer everything.

Where the HESI differs from the TEAS

  • Maths leans applied. Expect conversions, ratios and dosage-shaped word problems rather than abstract algebra.
  • Vocabulary is its own section. The TEAS folds vocabulary into English & Language Usage; the HESI gives it ~50 questions of its own, so a word list genuinely pays here.
  • Science is split. Rather than one Science section, A&P, Biology and Chemistry are separate modules that your school selects individually.
  • Grammar is deeper. ~50 items versus the TEAS's 37-question English section.

How to study for it

Work section by section rather than mixing, because the sections are so different in character. Vocabulary and Grammar reward daily short reps — 15 minutes of flashcards beats a two-hour block once a week. A&P rewards structure: learn each system's parts and their function together, not as isolated terms.

CinnaEntry covers all seven academic HESI sections with 3,220 questions, plus cheat sheets for the A&P and chemistry topics that carry the most weight.

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