Sex-Linked InheritanceHESI A2 cheat sheet

Why it hits males harder

6 key facts 2 practice questions Reviewed Oct 2026

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The Setup

Females XX, males XY
Most sex-linked genes sit on the X chromosome

Why Males

A male has only one X — one recessive allele shows
A female needs both X's affected to express it

Carriers

A heterozygous female is a carrier with no symptoms

Examples

Red-green color blindness, hemophilia, Duchenne muscular dystrophy

Key takeaway

Why it hits males harder

Before you read

Test yourself first: 2 questions

Question 1 of 2

The building blocks of proteins, linked in chains, are:

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