CinnaEntry Start free
HESI VocabularyDecode a word you have never seen

Prefixes, Suffixes & RootsHESI A2 cheat sheet

Most medical terms are built from a small set of reusable parts.

23 key facts 5 practice questions Reviewed Oct 2026
The 1-minute sheetCinnaEntry

Prefixes

  • a-/an- without (apnea) · dys- difficult (dyspnea)
  • brady- slow · tachy- fast
  • hyper- above normal · hypo- below normal
  • peri- around · poly- many · sub- under

Suffixes

  • -itis inflammation · -ectomy surgical removal
  • -ostomy surgical opening · -oscopy looking inside
  • -emia blood condition · -pathy disease
  • -ology the study of · -pnea breathing

Roots

  • cardi- heart · pulmon- lung · hepat- liver
  • nephr-/ren- kidney · gastr- stomach
  • oste- bone · my- muscle · neur- nerve · derm- skin
Key takeaway

A term is usually prefix + root + suffix: the prefix modifies, the root names the body part, the suffix says what is happening to it.

Before you read

Test yourself first: 5 questions

Question 1 of 5

'Anuria' means:

What is prefixes, suffixes & roots?

Learning roughly thirty of them lets you decode words you have never seen — which pays off in the Vocabulary section AND in the Anatomy, Biology and Chemistry sections, where the same parts keep reappearing.

Key points

  • A term is usually prefix + root + suffix: the prefix modifies, the root names the body part, the suffix says what is happening to it.
  • Prefixes of amount and rate: a-/an- (without), hyper- (above normal), hypo- (below normal), brady- (slow), tachy- (fast), poly- (many).
  • Suffixes of process: -itis (inflammation), -ectomy (surgical removal), -ostomy (surgical opening), -oscopy (looking inside), -pathy (disease), -ology (study of).
  • Roots of place: cardi- (heart), pulmon- (lung), hepat- (liver), nephr-/ren- (kidney), gastr- (stomach), oste- (bone), my- (muscle), neur- (nerve), derm- (skin).
  • -emia means a blood condition, so anemia = without enough blood cells and hyperglycemia = high blood sugar.

Study first

  1. Decode 'bradycardia' cold: brady- (slow) + cardi- (heart) + -ia (condition) = a slow heart rate. You never needed to memorize the whole word.
  2. Decode 'hepatitis': hepat- (liver) + -itis (inflammation) = inflammation of the liver.

Commonly tested

  • Learn prefixes and suffixes FIRST — they are fewer than the roots and do more work.
  • Practice by splitting long words with a slash: peri/cardi/um, poly/ur/ia. If you can split it, you can define it.

Watch out for

  • Mixing up -ectomy (remove it) with -ostomy (make an opening) — one takes tissue out, the other creates a passage.
  • Reading hyper- and hypo- too quickly; they are two letters apart and mean opposite things.
  • Assuming every root is Latin — some are Greek, so two roots can name the same organ (nephr- and ren- are both kidney).

Prefixes, Suffixes & Roots: FAQs

What should I focus on first when studying Prefixes, Suffixes & Roots?

Decode 'bradycardia' cold: brady- (slow) + cardi- (heart) + -ia (condition) = a slow heart rate. You never needed to memorize the whole word. Decode 'hepatitis': hepat- (liver) + -itis (inflammation) = inflammation of the liver.

What is most often missed on Prefixes, Suffixes & Roots?

Mixing up -ectomy (remove it) with -ostomy (make an opening) — one takes tissue out, the other creates a passage. Reading hyper- and hypo- too quickly; they are two letters apart and mean opposite things. Assuming every root is Latin — some are Greek, so two roots can name the same organ (nephr- and ren- are both kidney).

What do I need to know about Prefixes, Suffixes & Roots for the HESI A2?

A term is usually prefix + root + suffix: the prefix modifies, the root names the body part, the suffix says what is happening to it. Prefixes of amount and rate: a-/an- (without), hyper- (above normal), hypo- (below normal), brady- (slow), tachy- (fast), poly- (many). Suffixes of process: -itis (inflammation), -ectomy (surgical removal), -ostomy (surgical opening), -oscopy (looking inside), -pathy (disease), -ology (study of). Roots of place: cardi- (heart), pulmon- (lung), hepat- (liver), nephr-/ren- (kidney), gastr- (stomach), oste- (bone), my- (muscle), neur- (nerve), derm- (skin).

What are the most commonly tested points on Prefixes, Suffixes & Roots?

Learn prefixes and suffixes FIRST — they are fewer than the roots and do more work. Practice by splitting long words with a slash: peri/cardi/um, poly/ur/ia. If you can split it, you can define it.

CinnaEntry website
CinnaEntry app: the study feed with a practice question
Study Prefixes, Suffixes & Roots in the appTEAS 7 and HESI A2 question banks with a rationale on every answer and timed practice tests.See how CinnaEntry works
Start free
Want more HESI Vocabulary questions?We'll email you a free set on Prefixes, Suffixes & Roots. No account needed.

Was this helpful?

Free to start

Know prefixes, suffixes & roots cold

TEAS 7 and HESI A2 question banks with a rationale on every answer and timed practice tests.

  • TEAS 7 & HESI A2 question banks
  • Rationale on every answer
  • Timed full-length practice tests
  • 300+ cheat sheets
See how CinnaEntry works
CinnaEntry website
CinnaEntry app: the study feed with a practice question