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HESI A2 Chemistry Practice Questions

15 free questions from the CinnaEntry HESI A2 chemistry bank (233 in the app). Tap an answer to check it. The rationale opens right away.

15 questions Rationale on every answer Updated October 17, 2026
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  1. Q1 / 15 Correct Not quite

    In a solution, the substance that is dissolved is called the:

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    Answer: B. Solute

    The solute is dissolved into the solvent (e.g., salt is the solute in salt water).

  2. Q2 / 15 Correct Not quite

    Which is a noble gas, unreactive because its outer shell is full?

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    Answer: A. Helium

    Noble gases (helium, neon, argon) sit in the final column with full outer shells. A full shell means no drive to react.

  3. Q3 / 15 Correct Not quite

    In the reaction 2H₂ + O₂ → 2H₂O, the substances on the LEFT are called:

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    Answer: A. Reactants

    Reactants → products, always left to right. The arrow means 'becomes'.

  4. Q4 / 15 Correct Not quite

    In H₂O, the subscript 2 means there are two atoms of:

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    Answer: B. Hydrogen

    The 2 applies to hydrogen, so water has two hydrogen atoms and one oxygen atom.

  5. Q5 / 15 Correct Not quite

    Which temperature scale has 0° as the freezing point of water?

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    Answer: A. Celsius

    Celsius 0 and 100 are water's freezing and boiling points. Kelvin uses the same size degree but starts at absolute zero.

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  7. Q6 / 15 Correct Not quite

    In the 'lock-and-key' model, an enzyme's shape must match its:

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    Answer: B. Substrate

    An enzyme's active site fits a specific substrate, like a key in a lock.

  8. Q7 / 15 Correct Not quite

    The elements on the left and center of the periodic table are mostly:

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    Answer: B. Metals

    Most elements are metals, found on the left and center of the periodic table.

  9. Q8 / 15 Correct Not quite

    To measure the mass of a small rock, the best tool is a:

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    Answer: A. Balance

    A balance measures mass by comparison with known masses.

  10. Q9 / 15 Correct Not quite

    The atomic number of an element tells you the number of:

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    Answer: A. Protons

    Atomic number = protons. Mass number = protons + neutrons. Change the protons and you have a different element; change the neutrons and you have an isotope.

  11. Q10 / 15 Correct Not quite

    Cooling water vapor until it becomes liquid is called:

    Show answer and rationale

    Answer: B. Condensation

    Condensation is a gas cooling into a liquid.

  12. Q11 / 15 Correct Not quite

    Mixing sand and salt, then dissolving the salt and filtering, separates them by:

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    Answer: B. Physical means

    Filtering and dissolving are physical methods to separate a mixture.

  13. Q12 / 15 Correct Not quite

    In a chemical formula, a COEFFICIENT written in front (as in 3H₂O) indicates:

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    Answer: A. The number of molecules

    3H₂O = three molecules, each containing 2 hydrogen and 1 oxygen — six hydrogen and three oxygen atoms in total.

  14. Q13 / 15 Correct Not quite

    When an acid and a base react together, they produce:

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    Answer: A. A salt and water

    Acid + base → salt + water. Antacids work this way, neutralizing excess stomach acid.

  15. Q14 / 15 Correct Not quite

    Which laboratory measurement would you record in milliliters?

    Show answer and rationale

    Answer: A. The volume of a liquid

    Match quantity to unit: volume in mL or L, mass in g or kg, length in m, temperature in °C. Unit questions are free marks.

  16. Q15 / 15 Correct Not quite

    Which gas produced by burning fossil fuels contributes to air pollution?

    Show answer and rationale

    Answer: B. Carbon dioxide

    Burning fossil fuels releases carbon dioxide, a greenhouse gas and pollutant.

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