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HESI VocabularyPrefix, root, combining vowel, suffix

Building Medical WordsHESI A2 cheat sheet

Prefix, root, combining vowel, suffix

9 key facts 3 practice questions Reviewed Oct 2026
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The Parts

  • Prefix modifies the beginning
  • Root carries the core meaning
  • Combining vowel (usually o) joins parts
  • Suffix gives the condition or procedure

The Rule

  • Keep the combining vowel before a suffix starting with a consonant
  • Drop it before a suffix starting with a vowel
  • gastroscopy, but gastritis

Reading Order

  • Read the suffix first, then the prefix, then the root

Worked

  • Electrocardiogram = electro (electrical) + cardi (heart) + gram (record)
Key takeaway

Prefix, root, combining vowel, suffix

Before you read

Test yourself first: 3 questions

Question 1 of 3

'He gave a CONCISE report at the change of shift.' Concise means:

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