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TEAS ScienceChanges in the DNA sequence

MutationsATI TEAS 7 cheat sheet

Changes in the DNA sequence

8 key facts Reviewed Oct 2026
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Point Mutations

  • Substitution — one base swapped
  • Silent — no amino acid change
  • Missense — different amino acid
  • Nonsense — creates an early stop codon

Frameshift

  • Insertion or deletion shifts the whole reading frame
  • Usually far more damaging than a substitution

Causes

  • Replication errors, radiation, chemicals, some viruses

Effects

  • Harmful, neutral or occasionally beneficial — the raw material of evolution
Key takeaway

Changes in the DNA sequence

Common causes

  • Replication errors, radiation, chemicals, some viruses
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