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HESI Anatomy & PhysiologyHow a signal travels

Neuron Structure & the ImpulseHESI A2 cheat sheet

How a signal travels

9 key facts 5 practice questions Reviewed Oct 2026
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Parts

  • Dendrites receive · cell body integrates · axon transmits
  • Myelin sheath insulates; gaps are the nodes of Ranvier

Resting State

  • Inside is negative (~−70 mV)
  • High sodium outside, high potassium inside
  • Maintained by the sodium-potassium pump

Action Potential

  • Threshold reached → sodium rushes in (depolarization)
  • Potassium leaves (repolarization)
  • All-or-none — it either fires fully or not at all

Speed

  • Saltatory conduction jumps node to node — myelinated fibers are fastest
Key takeaway

How a signal travels

Before you read

Test yourself first: 5 questions

Question 1 of 5

A neurotransmitter crosses which structure to reach the next neuron?

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